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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC

Fig. 3

LCL161 and paclitaxel synergize to reduce cell viability in NSCLC cells. A549 and H460 lung cancer cells were treated for 48 h with the indicated concentrations of LCL161 (a) or paclitaxel (b). Cells were treated for 48 h with the indicated concentrations of LCL161 and paclitaxel (c) or for the indicated times with 10 μM LCL161 and/or 10 μM paclitaxel (d). Cell viability was determined by the MTT assay. Data are represented as mean ± SD; *P < 0.05; **P < 0.01; ***P < 0.001

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