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Table 3 Correlation between cIAP1, cIAP2 expression and clinicopathological characteristics

From: LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC

Variable n c-IAP1 P c-IAP2 P
Negative Positive Negative Positive
Gender
 Male 94 32 62 0.723 50 44 0.764
 Female 32 12 20   18 14  
Age
  ≤ 65 79 28 51 0.873 44 35 0.614
  > 65 47 16 31   24 23  
Histology
 Squamous cell carcinoma 51 19 32 0.661 30 21 0.665
 Adenocarcinoma 59 21 38   30 29  
 Others 16 4 12   8 8  
Tumor differentiation
 G1 15 7 8 0.591 8 7 0.176
 G2 67 22 45   41 26  
 G3 44 15 29   19 25  
Tumor location
 central type 69 24 45 0.971 40 29 0.321
 peripheral type 57 20 37   28 29  
Tumor size
 T1 32 13 19 0.423a 22 10 0.074a
 T2 77 28 49   39 38  
 T3 14 3 11   7 7  
 T4 3 0 3   0 3  
Lymph node metastasis
 N0 74 30 44 0.126 44 30 0.115
 N1 29 10 19   16 13  
 N2 23 4 19   8 15  
pTNM stage
 I 57 26 31 0.025* 34 23 0.084
 II 43 14 29   25 18  
 III 26 4 22   9 17  
Total 126 44 82   68 58  
  1. aFisher’s exact tests; *p < 0.05