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Table 3 Correlation between cIAP1, cIAP2 expression and clinicopathological characteristics

From: LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC

Variable

n

c-IAP1

P

c-IAP2

P

Negative

Positive

Negative

Positive

Gender

 Male

94

32

62

0.723

50

44

0.764

 Female

32

12

20

 

18

14

 

Age

  ≤ 65

79

28

51

0.873

44

35

0.614

  > 65

47

16

31

 

24

23

 

Histology

 Squamous cell carcinoma

51

19

32

0.661

30

21

0.665

 Adenocarcinoma

59

21

38

 

30

29

 

 Others

16

4

12

 

8

8

 

Tumor differentiation

 G1

15

7

8

0.591

8

7

0.176

 G2

67

22

45

 

41

26

 

 G3

44

15

29

 

19

25

 

Tumor location

 central type

69

24

45

0.971

40

29

0.321

 peripheral type

57

20

37

 

28

29

 

Tumor size

 T1

32

13

19

0.423a

22

10

0.074a

 T2

77

28

49

 

39

38

 

 T3

14

3

11

 

7

7

 

 T4

3

0

3

 

0

3

 

Lymph node metastasis

 N0

74

30

44

0.126

44

30

0.115

 N1

29

10

19

 

16

13

 

 N2

23

4

19

 

8

15

 

pTNM stage

 I

57

26

31

0.025*

34

23

0.084

 II

43

14

29

 

25

18

 

 III

26

4

22

 

9

17

 

Total

126

44

82

 

68

58

 
  1. aFisher’s exact tests; *p < 0.05
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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