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Table 4 Univariate Cox regression analysis of overall survival in NSCLC patients

From: LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC

Variable HR 95 % CI P-value
Gender 0.93 0.578–1.497 0.765
Age 0.968 0.628–1.493 0.884
Histology 1.015 0.747–1.379 0.926
Tumor differentiation 1.275 0.923–1.763 0.141
Tumor location 1.008 0.662–1.536 0.97
Tumor size 1.684 1.180–2.404 0.004*
Lymph node metastasis 1.891 1.460–2.451 <0.001*
pTNM stage 2.141 1.630–2.811 <0.001*
cIAP1 1.623 1.024–2.572 0.039*
cIAP2 1.388 0.912–2.111 0.126
cIAP1+/ cIAP2+ 1.965 1.287–3.000 0.002*
  1. HR hazard ratio, CI confidence interval, *p < 0.05