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Table 4 Univariate Cox regression analysis of overall survival in NSCLC patients

From: LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC

Variable

HR

95 % CI

P-value

Gender

0.93

0.578–1.497

0.765

Age

0.968

0.628–1.493

0.884

Histology

1.015

0.747–1.379

0.926

Tumor differentiation

1.275

0.923–1.763

0.141

Tumor location

1.008

0.662–1.536

0.97

Tumor size

1.684

1.180–2.404

0.004*

Lymph node metastasis

1.891

1.460–2.451

<0.001*

pTNM stage

2.141

1.630–2.811

<0.001*

cIAP1

1.623

1.024–2.572

0.039*

cIAP2

1.388

0.912–2.111

0.126

cIAP1+/ cIAP2+

1.965

1.287–3.000

0.002*

  1. HR hazard ratio, CI confidence interval, *p < 0.05