From: LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC
Variable | HR | 95Â % CI | P-value |
---|---|---|---|
Gender | 0.93 | 0.578–1.497 | 0.765 |
Age | 0.968 | 0.628–1.493 | 0.884 |
Histology | 1.015 | 0.747–1.379 | 0.926 |
Tumor differentiation | 1.275 | 0.923–1.763 | 0.141 |
Tumor location | 1.008 | 0.662–1.536 | 0.97 |
Tumor size | 1.684 | 1.180–2.404 | 0.004* |
Lymph node metastasis | 1.891 | 1.460–2.451 | <0.001* |
pTNM stage | 2.141 | 1.630–2.811 | <0.001* |
cIAP1 | 1.623 | 1.024–2.572 | 0.039* |
cIAP2 | 1.388 | 0.912–2.111 | 0.126 |
cIAP1+/ cIAP2+ | 1.965 | 1.287–3.000 | 0.002* |