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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Enhanced stimulation of anti-breast cancer T cells responses by dendritic cells loaded with poly lactic-co-glycolic acid (PLGA) nanoparticle encapsulated tumor antigens

Fig. 7

T cells proliferation responses induced by dendritic cells. Magnetic cell sorting (MACS)-enriched CD3+ T cells were stimulated with autologous DCs pulsed with a DCs treated with tumor antigen pulsed nanoparticles fabricated using three different amounts (concentrations) of PVA, b Comparison of DCs pulsed with nanoparticles containing tumor antigen with those pulsed with either tumor lysate or NPs alone, at a ratios of 5:1, 10:1 and 20:1 for five days and proliferation rates were meassured by MTT assay. The triplicate proliferation indices from three patients were averraged and expressed as mean ±S.D (n = 3) (P 0.05)

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