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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer

Fig. 2

TRIM62 was frequently down-regulated in CC and was significantly correlated with overall survival and disease-free survival. NCT, normal cervical tissue; CC, cervical cancer; SCC, squamous cell carcinoma; AC, adenocarcinoma. a Representative IHC images of CC tissues (SCC and AC) with different staining intensity (upper). Representative IHC images of NCT were conducted as control (lower), in which both squamous and glandular epithelial cells were stained throughout the cytoplasm, and the red arrows indicated the squamous epithelial cells and the blue arrows indicated the glandular epithelial cells. Original magnification: ×100, ×200 and × 400. Bar graph shows statistics for high/low expression of NCT, SCC and AC in the training and validation cohorts. b Survival curve was calculated with Log-rank test. The results showed the overall survival and disease-free survival of patients with high or low TRIM62 expression in the training cohort, validation cohort and overall cohort. P value was shown in each panel respectively

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