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Table 2 Univariate and Multivariate Analysis of Factors Associated with Overall Survival and Disease-Free Survival in Training Cohort

From: Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer

Clinicopathologic Variable Total OS DFS
Univariate Multivariate Analysis Univariate Multivariate Analysis
P RR (95 % CI) P P RR (95 % CI) P
Age(years)
42 61       
  > 42 47 0.424 n.a. n.a. 0.454 n.a. n.a.
FIGO stage
 Ia2 9   1    1  
 Ib1 53       
 Ib2 21       
 IIa1 12       
 IIa2 13 <0.001 1.697(1.128–2.555) 0.011 <0.001 1.681(1.148–2.463) 0.008
Tumor size(cm)
4 74   1     
  > 4 34 0.035 0.650(0.203–2.078) 0.467 0.068 n.a. n.a.
Pathologic types
 Squamous cell carcinoma 68       
 Adenocarcinoma 40 0.688 n.a. n.a. 0.921 n.a. n.a.
Differentiation grade
 Well 9       
 Moderate 48       
 Poor 51 0.209 n.a. n.a. 0.117 n.a. n.a.
Stromal invasion
  < 1/2 61   1    1  
1/2 47 0.011 1.740(0.535–5.662) 0.357 0.012 1.327(0.507–3.474) 0.565
Lymphovascular space invasion
 Yes 14      1  
 No 94 0.115 n.a. n.a. 0.046 0.629(0.190–2.080) 0.447
Pelvic-lymph node metastasis
 Yes 18   1    1  
 No 90 0.029 1.609 (0.646–4.011) 0.307 0.014 2.211(0.788–6.206) 0.132
Vaginal involvement
 Yes 4       
 No 104 0.824 n.a. n.a. 0.862 n.a. n.a.
Parametrial infiltration
 Yes 3       
 No 105 0.434 n.a. n.a. 0.505 n.a. n.a.
TRIM62
 low 67   1    1  
 high 41 0.008 0.200(0.046–0.873) 0.032 0.005 0.168(0.039–0.728) 0.017
  1. Abbreviations: n.a. Not application, FIGO the International Federation of Gynecology and Obstetrics; The bold number inside the table reflected < 0.05