Fig. 7
The anti-tumor effects of miR-193a in tumor xenograft. About 1 × 107 viable A549 cells transfected with pLVX-miR-193a (A549-miR-193a) or pLVX-miR-NC (A549-miR-NC) were subcutaneously injected into right flank of each nude mouse. n = 7. a A photograph of tumors from mice inoculated with A549-miR-193a or A549-miR-NC. b Volumes of all tumors were detected every 3 days after 2 weeks. c Volumes of all tumors were measured when the experiment was terminated at six weeks after tumor cell inoculation. d Net weights of all tumors were measured at the termination of the experiment. e The protein levels of WT1 and E-cadherin were detected in two tumor lysates from mice inoculated with A549-miR-193a or A549-miR-NC. f IHC staining of WT1 and E-cadherin was done in tumor xenografts from mice inoculated with A549-miR-193a or A549-miR-NC cells. Scale bar = 50 μm