Fig. 3
From: Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma
Apoptosis in a xenotransplantation model is increased after aflibercept treatment. a Fluorescence photomicrographs of TUNEL staining (green) in tumor tissue sections. b Quantification of TUNEL staining. The number of TUNEL-positive cells was significantly increased in the aflibercept group compared with the saline-injected group (# P < 0.005). Original magnification, ×400; scale bar, 200 μm