Skip to main content

Table 4 Univariate and multivariate analyses of miR-589-5p and other factors associated with survival (n = 40)

From: miR-589-5p inhibits MAP3K8 and suppresses CD90+ cancer stem cells in hepatocellular carcinoma

  DFS OS
Variables HR (95 % CI) p Value HR (95 % CI) p Value
Univariate analyses
Gender (male) 0.935 (0.320-2.732) 0.902 0.790 (0.245-2.548) 0.693
Age (≥60y) 0.979 (0.936-1.024) 0.349 1.015 (0.970-1.062) 0.513
HBsAg (positive) 1.041 (0.277-3.916) 0.952 3.165 (0.659-15.196) 0.150
AFP (high) 1.663 (0.718-3.852) 0.235 1.342 (0.530-3.396) 0.535
Vascular Invasion (positive) 1.911 (0.666-5.480) 0.228 1.052 (0.314-3.5181) 0.935
Tumer Size(≥5 cm) 1.157 (1.057-1.266) 0.002 1.190 (1.072-1.321) 0.001
Edmondson Grade (III/IV) 4.350 (1.979-9.561) 0.000 2.975 (1.335-6.631) 0.008
miR-589-5pLow 1.269 (1.095-1.470) 0.002 1.226 (1.090-1.469) 0.002
Multivariate analyses
Tumer Size(≥5 cm) 1.067 (0.949-1.201) 0.279 1.124 (0.984-1.285) 0.085
Edmondson Grade (III/IV) 2.800 (1.140-6.877) 0.025 1.573 (0.648-3.816) 0.317
miR-589-5pLow 1.230 (1.028-1.470) 0.023 1.190 (1.002-1.414) 0.048