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Table 4 Univariate and multivariate analyses of miR-589-5p and other factors associated with survival (n = 40)

From: miR-589-5p inhibits MAP3K8 and suppresses CD90+ cancer stem cells in hepatocellular carcinoma

 

DFS

OS

Variables

HR (95 % CI)

p Value

HR (95 % CI)

p Value

Univariate analyses

Gender (male)

0.935 (0.320-2.732)

0.902

0.790 (0.245-2.548)

0.693

Age (≥60y)

0.979 (0.936-1.024)

0.349

1.015 (0.970-1.062)

0.513

HBsAg (positive)

1.041 (0.277-3.916)

0.952

3.165 (0.659-15.196)

0.150

AFP (high)

1.663 (0.718-3.852)

0.235

1.342 (0.530-3.396)

0.535

Vascular Invasion (positive)

1.911 (0.666-5.480)

0.228

1.052 (0.314-3.5181)

0.935

Tumer Size(≥5 cm)

1.157 (1.057-1.266)

0.002

1.190 (1.072-1.321)

0.001

Edmondson Grade (III/IV)

4.350 (1.979-9.561)

0.000

2.975 (1.335-6.631)

0.008

miR-589-5pLow

1.269 (1.095-1.470)

0.002

1.226 (1.090-1.469)

0.002

Multivariate analyses

Tumer Size(≥5 cm)

1.067 (0.949-1.201)

0.279

1.124 (0.984-1.285)

0.085

Edmondson Grade (III/IV)

2.800 (1.140-6.877)

0.025

1.573 (0.648-3.816)

0.317

miR-589-5pLow

1.230 (1.028-1.470)

0.023

1.190 (1.002-1.414)

0.048