Fig. 1From: HPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instabilityChromosome translocation events identified by sequencing in this study. The ideograms for the architectures of viral-cellular junctions (left) and the location of fusion DNA on chromosomes (right) were shown for junctions S2-25:J-03 (a), S2-25:J-04 (b) and C5-87:J-08 (c) respectively. The HPV16 viral fragment was shown in purple rectangle, cellular fragments were shown in orange or green rectangle. The gene structure of SCAI and NR3C2 genes were shown in (a) below the ideogram of junction S2-25:J-03, the location of human fragment deriving from SCAI and NR3C2 genes were shown as green and red arrow respectivelyBack to article page