Skip to main content

Table 5 Overview of cancer related genes closely linked to HPV integration sites documented in Dr.VIS v2.0 database [72]

From: HPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instability

ID

Method

Disease

Subtype

Cytoband

Nearest gene

DRVIS03185

PCR

HNC

HPV16

1q25

TNFSF4

DRVIS03195

Exome-Seq

CC

HPV56

3q28

TP63

DRVIS03198

Mapping

CC

HPV16

1p36.32

TP73

DRVIS02845

RS-PCR

CC

HPV16

4q13.3

RASSF6

DRVIS00089

DIPS-PCR

CC

HPV16

2q21.2

ARHGEF4

DRVIS00246

DIPS-PCR

CC

HPV16

16q24

CDH13

  1. The ID of integration events in Dr.VIS v2.0 database, methods for the detection of viral integration, disease associated with samples, HPV subtype and integration locations were shown in column 1, 2, 3, 4, 5 and 6 respectively. HNC, head and neck cancer; CC, cervical carcinoma; Exome-Seq, Exome sequencing; DIPS-PCR, detection of integrated papillomavirus sequences by ligation-mediated PCR; RS-PCR, RNA Template-Specific PCR; Mapping, mapping analysis. TNFSF4 (tumor necrosis factor superfamily member 4), TP63 (tumor protein p63), TP73 (tumor protein p73), ARHGEF4 (Rho guanine nucleotide exchange factor 4), CDH13 (cadherin 13), RASSF6 (Ras association domain family member 6)