Fig. 4
From: GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment
GANT61 increased TMZ-induced invasion in glioma cells. Cell invasion was analyzed using the Transwell assay. Transwell assay showed the invasive capability of (a) U251 and (b) U87 cells treated with GANT61, TMZ and the combination therapy. GANT61 or TMZ reduced the invasion of glioma cells and their combination showed much lower invasion as demonstrated by representative microscope graphs (10 × 30). *P < 0.05, **P < 0.01 compared with control group. The results were presented as the mean of three independent experiments