Fig. 1

OL enhances radiosensitivity of NPC cells both in vitro and in vivo. a and b Viability of NPC cells HNE-1 (a) and HONE-1 (b) were assessed, after incubation with media containing 0 or 200 μM of OL for 24 h, respectively, and then subjected to radiation dosage as indicated. c Experimental time line of the xenograft mouse model, with cell injection performed on day 0 and irradiation (IR, 12 Gy) performed on both day 7 and 14. d and e Growth curve of HNE-1 (d) and HONE-1 (e) xenograft tumors in mice after mock or OL treatment, respectively (n = 10 each). Values were expressed as mean ± SD. * p < 0.05, ** p < 0.01, compared to 0 μM OL. # p < 0.05, compared to mock treatment