From: Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness
 | Netrin-1 expression | ||
---|---|---|---|
 | Negative | Positive | P value |
Histological type | n = 55, % = 40.4 | n = 81, % = 59.6 |  |
 Astrocytoma | 8 (22.2) | 28 (77.8) | <.0001 |
 Anaplastic astrocytoma | 6 (37.5) | 10 (62.5) |  |
 Oligodendroglioma | 22 (73.3) | 8 (26.7) |  |
 Oligoastrocytoma | 12 (63.2) | 7 (36.8) |  |
 Glioblastoma | 8 (22.9) | 27 (77.1) |  |
Gender | |||
 Female | 27 (43.5) | 35 (56.5) | .499 |
 Male | 28 (37.8) | 46 (62.2) |  |
Grade | |||
 II | 35 (49.3) | 36 (50.7) | .033 |
 III | 12 (40.0) | 18 (60.0) |  |
 IV | 8 (22.9) | 27 (77.1) |  |
Nestin expression | |||
 Negative | 14 (51.9) | 13 (48.1) | .014 |
 Positive | 20 (26.0) | 57 (74.0) |  |
 NA | 21 | 11 |  |
Age at the time of diagnosis | |||
 Median/range, years | 41 (23–76) | 44 (17–75) | .386 |