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Table 1 Association between expression of CIP4 and clinicopathological characteristics in 169 NPC patients

From: CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling

Clinical factor

Cases (n = 169)

CIP4 expression

P value

High

Low

(n = 83)

(n = 86)

Gender

 Male

128

63

65

0.961

 Female

41

20

21

Ages (years)

 < 45

79

39

40

0.951

 ≥ 45

90

44

46

T stage

 T1-2

49

22

27

0.484

 T3-4

120

61

59

N stage

 N0-1

89

41

48

0.404

 N2-3

80

42

38

M stage

 M0

160

75

85

0.035

 M1

9

8

1

Clinical stage

 I-II

17

6

11

0.229

 III-IV

152

77

75

WHO histological classification Type 2

 Differentiated

8

2

6

0.300

 Undifferentiated

161

81

80

Local-regional relapse

 No

166

81

85

0.975

 Yes

3

2

1

Distant metastasis

 No

156

73

83

0.072

 Yes

13

10

3

Progression

 No

147

66

81

0.005

 Yes

22

17

5

Death

 No

142

63

79

0.005

 Yes

27

20

7

  1. Statistical significance (p < 0.05) is shown in bold and italic