Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes tumorigenesis and metastasis by targeting miR-199a/b-5p in hepatocellular carcinoma

Table 4 Correlation between SNHG12 expression and clinicopathological variables of HCC patients

Variable	Total no. (n = 48)	Relative SNHG12 expression		P value
Variable	Total no. (n = 48)	High (n = 24)	Low (n = 24)	P value
Gender
Male	37	19	18	0.7313
Female	11	5	6
Age (years)
<60	23	10	13	0.3861
≥60	25	14	11	0.3861
Tumor size (cm)
<5	20	6	14	0.0192*
≥5	28	18	10	0.0192*
Serum AFP (ng/ml)
<200	9	4	5	1.0000
≥200	39	20	19	1.0000
Liver cirrhosis
Present	25	15	10	0.1486
Absent	23	9	14	0.1486
Vascular invasion
Present	23	16	7	0.0093*
Absent	25	8	17	0.0093*
PVTT
Present	8	5	3	0.7008
Absent	40	19	21	0.7008
Differentiation
Well	7	4	3	0.6327
Moderate	33	15	18
Poor	8	5	3
TNM stage
I–II	22	7	15	0.0415*
III–IV	26	17	9	0.0415*

Abbreviation: AFP α-fetoprotein, PVTT, portal vein tumor thrombus, TNM tumor-node-metastasis
* P < 0.05

ISSN: 1756-9966