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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer

Fig. 1

The effects of DOX and RES on gastric cancer cells. a CCK8 assay was used to detect the chemo-sensitiviy of SGC7901 and MGC803 cells to DOX treatment. Survival rate = (mean absorbance of experimental group/mean absorbance of control group) × 100%. The survival inhibition effect of doxorubicin demonstrated a dose (Factorial ANOVA, p < 0.001) and time-dependent (Factorial ANOVA, p < 0.001) manner, except that the difference between 10 mg/L and 5 mg/L (p = 0.910) and that between day 4 and day 5 (p = 0.300) were not significant. b The reveratrol concentration gradient ranges from 10 mg/L to 200 mg/L. The survival inhibition effect of resveratrol on SGC7901 cells demonstrated a dose (Factorial ANOVA, p < 0.001) and time-dependent (Factorial ANOVA, p < 0.001) manner. Also, the survival inhibition effect of resveratrol on MGC803 cells demonstrated a dose (Factorial ANOVA, p < 0.001) and time-dependent (Factorial ANOVA, p < 0.001) manner when resveratrol concentration was over 20 mg/L

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