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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Intracellular pH-responsive and rituximab-conjugated mesoporous silica nanoparticles for targeted drug delivery to lymphoma B cells

Fig. 2

pH-responsive release profiles of DOX from the DMSNs and RDMSNs in medium and PBS solution (pH 5.0 and pH 7.4) over 48 h, respectively. These results indicated that the DOX released from nanoparticles was more at a pH of 5.0 than that at a pH of 7.4 or medium. RDMSNs (PBS pH7.4) vs RDMSNs (PBS pH5.0) (a), DMSNs (PBS pH7.4) vs DMSNs (PBS pH5.0) (b), RDMSNs (PBS pH 5.0) vs RDMSNs (medium) (c), and DMSNs (PBS pH 5.0) vs DMSNs (medium) (d). Data are presented as mean ± SD from three independent experiments. *, P < 0.05; **, p < 0.01

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