Fig. 5

Kaplan–Meier estimates of NSCLC patient survival according to the stimulated endothelial cell gene signatures. a, b Kaplan-Meier estimates of overall survival (n = 293) (a) and disease-free survival (n = 278) (b) of the subjects who were categorized based on the 11-gene signature derived from the differentially expressed genes of HUVECs co-cultured with cancer cells. c, d Kaplan-Meier estimates of overall survival (n = 293) (c) and disease-free survival (n = 278) (d) of the subjects who were categorized based on the 5-gene signature derived from the differentially expressed genes of HUVECs co-cultured with cancer cells. The datasets were obtained from GSE30219. The survival curve was estimated by the Kaplan-Meier method, and the log-rank test was performed to test the difference between the survival curves