Table 2 Multivariate Cox regression analysis of two gene set signatures for the overall survival of patients with NSCLC

 Median of risk score

1.425

1.073

1.892

0.0143

 Gender

1.460

0.926

2.300

0.1031

 Age

1.037

1.022

1.052

<0.0001

 Stage (0.1.2 vs. 3.4)

2.990

2.185

4.092

<0.0001

 Median of risk score

1.341

0.997

1.803

0.0521

 Gender

1.485

0.930

2.371

0.0974

 Age

1.036

1.020

1.051

<0.0001

 Stage (0.1.2 vs. 3.4)

2.941

2.116

4.087

<0.0001

 Median of risk score

1.414

1.063

1.882

0.0172

 Gender

1.455

0.923

2.293

0.1060

 Age

1.037

1.022

1.052

<0.0001

 Stage (0.1.2 vs. 3.4)

2.922

2.134

3.999

<0.0001

 Median of risk score

1.356

1.009

1.823

0.0435

 Gender

1.489

0.933

2.375

0.0950

 Age

1.036

1.021

1.051

<0.0001

 Stage (0.1.2 vs. 3.4)

2.903

2.087

4.037

<0.0001