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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Buformin inhibits the stemness of erbB-2-overexpressing breast cancer cells and premalignant mammary tissues of MMTV-erbB-2 transgenic mice

Fig. 7

Buformin targets cancer stem cell/tumor-initiating cell populations in premalignant tissues from MMTV-erbB-2 mice. As detailed above, isolated MECs were labeled with CD61/CD49f markers and analyzed with flow cytometry (N = 4). a The percentage of CD61highCD49fmid cell populations were compared between the control and buformin-fed mice with representative CD61/CD49f flow cytometry plots shown in b. All values are depicted in the graph as the mean ± S.E. (**p < 0.01)

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