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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: E2F8, a direct target of miR-144, promotes papillary thyroid cancer progression via regulating cell cycle

Fig. 3

Knockdown of E2F8 inhibits tumor growth in vivo. a Xenograft model in nude mice. b Nodules harvested from shRNA-NC group and E2F8-KD group. c and d Tumor nodules derived from shRNA-E2F8-transfected TPC-1 cells are significantly smaller than those in shRNA-NC group. e IHC analysis of xenograft tumors showed that Ki-67 staining was weaker in shRNA-E2F8 group. *p < 0.05, **p < 0.01, ***p < 0.001

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