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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: E2F8, a direct target of miR-144, promotes papillary thyroid cancer progression via regulating cell cycle

Fig. 8

miR-144 is downregulated in PTC tissues and inversely correlates with E2F8 expression. a TCGA dataset showed that miR-144 was significantly downregulated in PTC tissues compared with adjacent normal tissues. b qRT-PCR analysis showed that miR-144 was significantly decreased along with more advanced T stage in PTC tissues. U6 was used as an internal control to normalize expression data. c Pearson correlation scatter plot of fold change in miR-144 levels and E2F8 mRNA levels in PTC tissues (n = 64). d A hypothetical model of the miR-144/E2F8/CCND1 axis controlling PTC cell proliferation. ***p < 0.001, # No significance

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