Fig. 4

a Heatmap and clustering analysis according to immunophenotypic markers expression correlated with poor prognosis genetic signature. Note that at the bottom of heatmap it is shown that patients in green group are those with lower altered expression of ID1, ID3, IGJ genes. While most patients with overexpression of two or more of these genes are included in the red group. Kaplan-Meier curves for event-free survival (p = 0.001) b and overall survival (p = 0.045) c according to the groups defined by the heatmap in a