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Table 2 Xenotransplantation of cells into NOD/SCID mice

From: Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma

Cells + Treatment Inoculum size Tumor incidence Tumor volume (mm3)
ACHN
cell line
Caki-1
cell line
ACHN
cell line
Caki-1
cell line
Parental cells 1 × 105 6/6 6/6   
1 × 104 4/6 5/6 501.17 ± 46.31 544.67 ± 62.26
1 × 103 1/6 1/6   
CSCs 1 × 105 6/6 6/6   
1 × 104 6/6 6/6 774.67 ± 54.04 756.67 ± 70.32
1 × 103 3/6 3/6   
CSCs + MRK003 1 × 105 5/6 5/6   
1 × 104 2/6 3/6 306.17 ± 56.56 378.50 ± 38.34
1 × 103 0/6 1/6   
CSCs + Numb 1 × 105 5/6 5/6   
1 × 104 3/6 3/6 317.17 ± 82.34 377.50 ± 51.93
1 × 103 0/6 1/6