Fig. 3

Tigecycline inhibits energy metabolism in CML cells. (a) Mitochondrial respiration of the CML cells was measured before and after treatment with tigecycline, and is represented by the oxygen consumption rate (OCR) curve and values. Oligo, oligomycin; A&R, antimycin A and rotenone. (b) Effect of tigecycline on glycolysis in the CML cells. Glycolysis capacities of the CML cells are shown by the extracellular acidification rate (ECAR) curves and values. Oligo, oligomycin. *P < 0.05