Fig. 1

SOX3 is upregulated in human osteosarcoma tissues. a, b Relative SOX3 mRNA and protein levels were significantly increased in osteosarcoma tissues when compared with the adjacent non-tumor tissues (n = 42). c Relative SOX3 mRNA level was significantly higher in osteosarcoma tissues (n = 42) than that in bone cysts (n = 28). d, e SOX3 mRNA and protein levels in different OS cell lines. Data represent the mean ± SD of triplicate samples; *P < 0.05, **P < 0.01