Fig. 2

SOX3 promotes OS cell migration and invasion. a SOX3 overexpression in MG63 cells and successful knockdown of SOX3 in U2OS cells were confirmed by western blot and qRT-PCR. b Wound-healing migration assays and the distance quantification of wound closure. c The invasive OS cells and quantitation of invasive OS cell counts. d The lung metastatic foci were photographed. Representative views of lung tissue section are shown. The results are expressed as the mean ± SD of triplicate samples; * P < 0.05, **P < 0.01