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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2

Fig. 6

Downregulation of miR-27a inhibits tumor growth and metastasis in vivo. a Time-dependent tumor volumes in the negative control and the miR-27a antagomir groups. **P < 0.01 and ***P < 0.001. Photographs of tumors derived from nude mice in the NC and the miR-27a antagomir groups. b Average weight of tumors from nude mice. *P < 0.05. c Representative photographs of immunohistochemical analysis of Ki-67 and PHLPP2 in tumors from nude mice. d Macroscopic observation in the livers and representative images of liver metastases (H&E staining). e Schematic presentation of miR-27a and PHLPP2 in the progression of gastric cancer

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