Fig. 6

NKILA regulate NSCLC cell mobility via NF-κB/Snail pathway. (a and b) The expression levels of classical EMT markers in A549 (a) and H226 (b) cells were measured by western blot. (c and d) Migration and invasion ofA549 and H226 stably expressing NKILA or mock-vehicle control with or without TNFα stimuli measured by Chamber assay. (e and f) Migration and invasion of A549 and H226 stably expressing NKILA shRNA or negative control with or without JSH-23 (JSH) measured by Chamber assay. Left panel was representative images and right panel was statistical column diagram. Data are expressed as means ± SEM, n = 3. *p < 0.05, **p < 0.01, ***p < 0.001