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Table 2 Univariate and Multivariate Analysis of Factors Associated with Overall Survival

From: The long non-coding RNA TP73-AS1 modulates HCC cell proliferation through miR-200a-dependent HMGB1/RAGE regulation

Variable n Univariate Analysis Multivariate Analysis
P HR (95% CI) P HR (95% CI)
Age (year)   0.162   N.A  
 <50 45   1.011 (1.000–1.034)   
 ≥50 39   1   
Gender   0.856   N.A  
 Female 26   1   
 Male 58   1.062 (0.561–2.013)   
Tumor size (cm)   0.39   N.A  
 <5 40   0.771 (0.424–1.397)   
 ≥5 44   1   
Tumor nodule number   0.04   0.664  
 Multiple (≥2) 43   1.910 (1.033–3.564)   1.166 (0.583–2.333)
 Solitary 41   1   1
Venous invasion   0.522   N.A  
 Absence 37   1   
 Presence 47   1.217 (0.671–2.224)   
TNM   0.038   0.045  
 I + II 33   0.508 (0.217–0.963)   0.516 (0.261–0.902)
 III + IV 56   1   1
BCLC staging   0.029   0.129  
 0-A 24   0.322 (0.122–0.891)   0.442 (0.154–1.267)
 B 23     
 C 24     
 D 15   1   1
Liver function   0.696   N.A  
 Child-Pugh A 41   1   
 Child-Pugh B 43   1.131 (0.623–2.054)   
TP73-AS1 expression   0.005   0.019  
 Higher 42   2.427 (1.311–4.533)   2.249 (1.141–4.430)
 Lower 42   1   1