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Table 1 Association between AHNAK and clinicopathological characteristics in triple-negative breast cancer

From: AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer

Variables

Cases

Ahnak

P value

(n = 221)

high

No. (%)

low

No. (%)

Age (years)

     

0.586

 <50

133

66

49.6%

67

50.4%

 

 ≥50

88

47

53.4%

41

46.6%

 

Menopause

     

0.338

 yes

90

50

55.6%

40

44.4%

 

 no

131

63

48.1%

68

51.9%

 

 BMI

     

0.156

 <25

169

91

53.8%

78

46.2%

 

 ≥25

52

22

42.3%

30

57.7%

 

Tumor status (T)

     

0.015*

 T1

67

42

62.7%

25

37.3%

 

 T2

120

61

50.8%

59

49.2%

 

 T3

17

6

35.3%

11

64.7%

 

 T4

17

4

23.5%

13

76.5%

 

Lymph node status (N)

     

<0.001*

 N0

117

80

68.4%

37

31.6%

 

 N1

57

21

36.8%

36

63.2%

 

 N2

35

9

25.7%

26

74.3%

 

 N3

12

3

25.0%

9

75.0%

 

Histological grade

     

0.139

 G1 + G2

108

61

56.5%

47

43.5%

 

 G3

113

52

46.0%

61

54.0%

 

LN infiltration

     

<0.001*

 No

117

80

68.4%

37

31.6%

 

 Yes

104

33

31.7%

71

68.3%

 

TNM stage

     

<0.001*

 I

48

34

70.8%

14

29.2%

 

 II

111

64

57.7%

47

42.3%

 

 III

56

14

25.0%

42

75.0%

 

 IV

6

1

16.7%

5

83.3%

 
  1. Abbreviation: BMI body mass index, LN lymph node
  2. *P < 0.05, statistically significant