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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Genotypes of SLC22A4 and SLC22A5 regulatory loci are predictive of the response of chronic myeloid leukemia patients to imatinib treatment

Fig. 3

Cumulative achievement of stable MMR and EFS during imatinib treatment in association with genotypes. a CCI of stable MMR in rs460089-GC, rs460089-CC and rs460089-GG genotypes; the data in the table indicate the probability of achieving MMR at 12, 18 and at 24 months of imatinib therapy for a particular genotype. b EFS in rs460089-GC, rs460089-CC and rs460089-GG genotypes. c CCI of stable MMR in rs460089-GC_rs2631365-TC vs rs460089-GG_rs2631365-TC genotypes. d EFS in rs460089-GC_rs2631365-TC vs rs460089-GG_rs2631365-TC genotypes. Events were defined as loss of response, BCR-ABL1 mutation, progression or death related to CML during imatinib treatment. The censored patients also included those whose treatment was switched to 2nd line TKIs. Graphical analysis was supplemented using the log-rank test

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