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Table 1 Correlations between expressions of SHH and GLI1 protein and clinicopathological factors

From: Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells

 

SHH expression

GLI1 expression

Clinical parameters

Low (n = 37)

High (n = 53)

χ2

p

Low (n = 50)

High (n = 40)

χ2

p

Gender

 Male

20

33

0.607

0.436

24

29

5.510

0.019*

 Female

17

20

26

11

Age

  < 60 years

13

22

0.373

0.542

15

20

3.740

0.053

  ≥ 60 years

24

31

35

20

Tumor size

  < 5.0 cm

14

21

0.029

0.864

21

14

0.458

0.498

  ≥ 5.0 cm

23

32

29

26

Tumor Location

 Fundus

5

6

0.241

0.886

6

5

0.477

0.788

 Body

15

20

21

14

 Antrum

17

27

23

21

Invasion depth

 T1,T2

4

10

1.077

0.383

11

3

3.557

0.080

 T3,T4

33

43

39

37

LNM

 Negative

11

12

0.575

0.448

13

10

0.012

0.914

 Positive

26

41

37

30

Metastasis

 Absent

35

51

0.137

1.000

48

38

0.052

1.000

 Positive

2

2

2

2

Vessel invasion

 Negative

28

33

1.795

0.180

36

25

0.918

0.338

 Positive

9

20

14

15

TNM stage

 I, II

14

26

1.111

0.292

21

19

0.272

0.602

 III, IV

23

27

29

21

  1. TNM Tumor, node, metastasis, LNM Lymph node metastasis
  2. *Significant difference