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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells

Fig. 6

Exosomal transfer of miR-21 enhances gastric cancer cells chemoresistance via the PTEN/PI3K/AKT signaling pathway. a qRT-PCR detection of PTEN in MFC cells treated with or without M2-Exo. (*** p < 0.001). b Western blot assays for the expression of PI3Kp85, PTEN, p-AKT, AKT, BCL-2 in MFC cells treated with or without M2-Exo.GAPDH was used as the loading control. c qRT-PCR detection of PTEN in MFC cells transfected with miR-21 mimics or miR-NC or without transfection (ctrl). d Western blot assays for the expression of PI3Kp85, PTEN, p-AKT, AKT, BCL-2 in MFC cells transfected with miR-21 mimics or miR-NC or without transfection (ctrl). GAPDH was used as the loading control

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