Fig. 1

Expression of miR-584-5p in GC tissues, GC cells and transfected cells. a. The expression levels of miR-584-5p in 75 pairs of human GC tissues and non-GC tissues were explored using miRNA RT-PCR. b. The expression levels of miR-584-5p in GC cells and GES-1 were detected by miRNA RT-PCR. c. Immunohistochemical staining against Ki-67 collected from GC patient samples showed a negative correlation between the expression of miR-584-5p and Ki67. d. miRNA RT-PCR was used to verify the expression of miR-584-5p in cells transfected with miR-584-5p-mimics and miR-584-5p-inhibitor lentivirus respectively. e, f. CCK-8 was used to determine the proliferation of GC cells transfected with miR-584-5p-mimics and miR-584-5p-inhibitor lentivirus. OD value between miR-584-5p-mimics or miR-584-5p-inhibitor and corresponding control group was significantly different at p < 0.001 by two-way ANOVA. *p < 0.05, **p < 0.01, ***p < 0.001. The data expressed as the mean ± SD