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Table 2 The correlation of VM with the clinicopathological parameter of HCC

From: HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment

Variants

VM

negative

positive

χ 2

P -value

Sex

 Male

131

38

1.137

2.286

 Female

22

10

Age

  < 50

39

19

3.535

0.060

  ≥ 50

114

29

Tumor size(cm)

  > 5

78

3

30.386

**

  ≤ 5

75

45

Grade

 I + II

88

8

24.437

**

 III + IV

65

40

Metastasis

 NO

77

1

35.810

**

 YES

76

47

  1. ** P <0.01
  2. In 48 specimens (23.88%), VM was observed. Notably, our results demonstrated that the presence of VM correlates with the tumor grade, metastasis, and poor prognosis
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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