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Table 2 The correlation of VM with the clinicopathological parameter of HCC

From: HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment

Variants VM
negative positive χ 2 P -value
Sex
 Male 131 38 1.137 2.286
 Female 22 10
Age
  < 50 39 19 3.535 0.060
  ≥ 50 114 29
Tumor size(cm)
  > 5 78 3 30.386 **
  ≤ 5 75 45
Grade
 I + II 88 8 24.437 **
 III + IV 65 40
Metastasis
 NO 77 1 35.810 **
 YES 76 47
  1. ** P <0.01
  2. In 48 specimens (23.88%), VM was observed. Notably, our results demonstrated that the presence of VM correlates with the tumor grade, metastasis, and poor prognosis