Fig. 7
From: FGF2/FGFR1 regulates autophagy in FGFR1-amplified non-small cell lung cancer cells
High levels of LC3B mRNA are associated with poor prognosis in NSCLC patients. a and b Kaplan-Meier curves of OS, with respect to LC3B mRNA level, in a lung SQCC (N = 146 for low expression and N = 146 for high expression, p = 0.014), and b lung adenocarcinoma (N = 123 for low expression and N = 123 for high expression, p = 0.5099). c Kaplan-Meier curves for OS in FGFR1 low - LC3B low expression (N = 125) and FGFR1 low - LC3B high expression (N = 119) patients, the latter had poorer OS (p = 0.0111). d Kaplan-Meier curves for OS in FGFR1 high - LC3B low expression (N = 119) and FGFR1 high - LC3B high expression (N = 124) patients, the latter conferred decreased OS (p = 0.1742). P-values are based on the log-rank test (a-d)