Fig. 6

Targeting FOXM1 reduces colony formation capacity and alters invasion in EOC cells. a 24 h after siRNA transfection, EOC cells were plated in 6-well plate, and then colonies were stained and counted after incubation for 7–9 days. Results are representative of three independent experiments. b The graphs provide quantification of numbers of colony forming cells. Each column represents mean ± SD of quintuplicate determinations. One way ANOVA, **, P ≤ 0.01, ***, P ≤ 0.001. c Representative images showing invaded cells (matrigel-coated membrane) after 24 h. d Graphic representation of invasion results as fold change of invaded cells in 3 fields of triplicate wells; data show mean and SD from four independent experiments. *, P ≤ 0.05, **, P ≤ 0.01, ***, P ≤ 0.001, one-way ANOVA test