Fig. 3

HSF1 promotes pancreatic cancer cell proliferation in vitro and in vivo. a and b The proliferation of ASPC-1, PANC-1 and their control cells was examined by CCK-8 assay. c and d Proliferation of ASPC-1, PANC-1 and their control cells was detected by colony formation assay. e Representative images of subcutaneous tumors in nude mice (n = 3 per group; total = 12 tumors). f Tumor weights. Differences were analyzed by paired t-test and data represent the mean ± standard deviation of three independent experiments. *P < 0.05, **P < 0.01