Fig. 3

GAEL sensitivity of EOC cells grown as spheroids. a MO-101 dose–response of primary EOC cell samples (EOC016B and H, EOC058). Cells were exposed to MO-101 for 72 h prior to determining cell viability. Data is shown as percent viability compared to vehicle treated controls. b Effect of MO-101 on EOC058 spheroid integrity after 96 h exposure. The right-hand panels show higher magnification images of the spheroids outlined by dashed boxes in the left panel