Fig. 6

AT2R decreases nasopharyngeal tumor growth in nude mice. a Representative fluorescence micrographs (10× view) showing eGFP fluorescence from bladder tumor; b At the end of the experiment, mice were sacrificed to obtain the tumors. The size of human bladder tumor xenografts from mice injected with Ad-G-AT2R-eGFP, Ad-CMV-eGFP or PBS was measured using a caliper and volume was calculated as follows: volume = (D × d²)/2, where D is the longest diameter and d is the shortest diameter. *, P < 0.01; n = 6; c growth curve of tumor volumes; d tumors from mice treated with Ad-G-AT2R-eGFP, Ad-CMV-eGFP or PBS were weighed at the time of sacrifice. *, P < 0.01; n = 6; e sections of transplanted tumors infused with Ad-G-AT2R-eGFP, Ad-CMV-eGFP or PBS were stained with Ki-67. Representative photomicrographs are shown to the left (magnification × 200). * P < 0.01 vs. the control groups