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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138

Fig. 4

a Heatmap illustrating the diversity of miRNA levels among 8 samples with the lowest ANGPTL1 mRNA level and 8 samples with the highest ANGPTL1 mRNA level. Among the miRNAs, the level of miR-138 was significantly higher in the samples with high levels of ANGPTL1 (P = 0.01). b Level of miR-138 in cells with overexpression and knockdown of ANGPTL1. In SW620-ANGPTL1 cells, the expression of miR-138 was significantly enhanced compared to control cells (P < 0.0001), while it was markedly inhibited in SW480-shANGPTL1 cells (P < 0.0001)

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