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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: MiR21 sensitized B-lymphoma cells to ABT-199 via ICOS/ICOSL-mediated interaction of Treg cells with endothelial cells

Fig. 4

ABT-199 counteracted miR21-mediated angiogenesis. a HUVEC cells were sorted from the co-culture system for further study, HUVEC growth was enhanced by miR21 overexpression and reduced by ABT-199 treatment in the co-culture systems of SU-DHL-4 and SU-DHL-8 cells. b-c ABT-199-mediated inhibition of HUVEC growth was associated with decreased tube formation (b) and increased HUVEC apoptosis, as revealed by TUNEL assay (c)

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