Table 3 Multivariate Cox proportional hazard models for overall survival (OS) and disease-free survival (DFS)

T stage (T1 + T2 vs. T3 + T4)

1.73 (1.09–4.01)

0.221

1.43 (0.35–5.52)

0.136

N stage (N0 vs. N1 + N2)

5.95 (3.62–9.22)

<0.001*

3.67 (1.59–7.44)

0.018*

M stage (N0 vs. M1)

4.04 (1.79–12.55)

0.014*

5.43 (1.69–20.04)

<0.001*

Differentiation (Well vs. Moderate + Poor)

2.99 (1.30–6.88)

0.025*

2.21 (1.05–9.62)

0.029*

NLRP3 (Low vs. High)

3.81 (0.36–8.08)

0.014*

1.88 (0.33–4.12)

0.194

NLRP3/Ki-67 (Both low vs. Both high)

7.79 (3.48–13.27)

<0.001*

12.27 (4.25–19.45)

<0.001*