Fig. 1

Cytotoxic effects of troglitazone (TGZ) and pioglitazone (PGZ) in two pancreatic cancer cell lines. MIA Paca2 or PANC-1 cells were pre-cultured for 24 h at a density of 1 × 10⁴ cells/well in 96-well plates and treated with TGZ or PGZ for 24 h. Cell viability was assessed by fluorescence assay, and data represent the mean ± SD from four independent preparations. Statistical significance was assessed by Dunnett’s test (control vs. each concentration of TGZ). * p < 0.05 and ** p < 0.01 vs. control (for TGZ). † p < 0.05 and †† p < 0.01 vs. control (for PGZ)