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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer

Fig. 6

In vivo antitumor effects of TGZ. a Tumor volume. Balb/c male mice were subcutaneously inoculated in the back with MIA Paca2 cells (5 × 106 cells) 14 days before the start of TGZ administration. Mice were then orally administered vehicle (control, n = 10) or 200 mg/kg of TGZ (n = 8) daily for 5 weeks. Tumor volume was measured bi-dimensionally and volume was calculated by the formula (length × width2) × 0.5. b Mouse body weights were monitored throughout the experiment. Data are presented as mean ± SD. * p < 0.05 and ** p < 0.01 vs. control on each individual day (t-test). TGZ, troglitazone

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