Fig. 1

CTHRC1 is frequently up-regulated in human breast cancer cells and tissues. a and b CTHRC1 was up-regulated in human breast cancer cells analyzed by qRT-PCR and western blot. *P < 0.05, **P < 0.01. c CTHRC1 mRNA in normal breast tissue, 5 benign breast tumor tissues and 18 paired breast cancer tissues detected by qRT-PCR. d CTHRC1 was significantly step-increased in benign breast tumor tissue, primary breast cancer tissues without LN metastasis and primary breast cancer tissues with LN metastasis. **P < 0.01. e CTHRC1 protein in normal breast tissue, 5 benign breast tumor tissues and 18 paired breast cancer tissues detected by western blot