Collagen triple helix repeat containing-1 negatively regulated by microRNA-30c promotes cell proliferation and metastasis and indicates poor prognosis in breast cancer

Table 1 The Correlations of CTHRC1 with Clinicopathological Features of Breast Cancer Patients

Clinicopathologic Variable	n	CTHRC1 expression		P
Clinicopathologic Variable	n	Low	High	P
Age(year)
≤ 45	35	13	22
>45	86	43	43	0.198
Histological grade
I	30	13	17
II- III	91	43	48	0.709
Positive lymph node
≤ 3	83	48	35
>3	38	8	30	<0.001
Lymphovascular invasion
Absence	73	46	27
Presence	48	10	38	<0.001
Tumor size(cm)
≤ 2	30	16	14
>2	91	40	51	0.372
ER
Positive	83	45	38
Negative	38	11	27	0.010
PR
Positive	57	32	25
Negative	64	24	40	0.040
Her2
Negative	67	33	34
Positive	54	23	31	0.465
TNM stage
I-II	79	46	33
III	42	10	32	<0.001

Abbreviations: ER estrogen receptor, PR progesterone receptor, Her2 Human Epidermal Growth Factor Receptor type 2, TNM tumor node metastasis
P < 0.05 was considered statistically significant

ISSN: 1756-9966