Fig. 5
miR-500a-3p promotes the tumorigenicity of hepatocellular carcinoma cells in vivo. a Representative images of tumors in xenograft model of nude mice. Tumors formed by overexpressed miR-500a-3p Huh 7cells grew quickly than the control tumors in the 1 × 105 and 1 × 104 cell group. Conversely, tumors formed by anti-miR-500a-3p cells were smaller than tumors formed by NC vector cells. Only miR-500a-3p-overexpressing cells formed tumors following implantation of 1 × 103 cells. b Histograms show the mean tumor weights of each group (n = 6 per group). *P < 0.05. (C-E) Growth curves for tumor formation after implantation. Mean tumor volumes are plotted